What percentage increase in risk for T2DM is associated with a BMI greater than 30?

What percentage increase in risk for T2DM is associated with a BMI greater than 30?

• A. 5 times
• B. 7 times for men, 12 times for women
• C. 10 times
• D. 20 times

Answer: (B)

A BMI greater than 30 is a defining criterion for obesity, which significantly increases the risk of developing type 2 diabetes mellitus (T2DM). The correct response indicates that men with a BMI over 30 have a 7-fold increased risk of developing T2DM, while women have a staggering 12-fold increase. This reflects the differential impact of obesity on metabolic health between genders, potentially due to differences in fat distribution, hormonal factors, and physiological responses. Research consistently shows that obesity is a major risk factor for T2DM due to its association with insulin resistance, increased inflammation, and changes in hormonal balance. Understanding this differential risk helps inform preventative strategies and can guide lifestyle interventions specific to gender, recognizing that women may require more targeted efforts to mitigate their heightened risk. The other answers suggest varying magnitudes of risk that do not align with the documented research findings, which show that specific risk increases for men and women are far more distinct, justifying the selection of the correct answer.

A BMI greater than 30 is a defining criterion for obesity, which significantly increases the risk of developing type 2 diabetes mellitus (T2DM). The correct response indicates that men with a BMI over 30 have a 7-fold increased risk of developing T2DM, while women have a staggering 12-fold increase. This reflects the differential impact of obesity on metabolic health between genders, potentially due to differences in fat distribution, hormonal factors, and physiological responses.

Research consistently shows that obesity is a major risk factor for T2DM due to its association with insulin resistance, increased inflammation, and changes in hormonal balance. Understanding this differential risk helps inform preventative strategies and can guide lifestyle interventions specific to gender, recognizing that women may require more targeted efforts to mitigate their heightened risk.

The other answers suggest varying magnitudes of risk that do not align with the documented research findings, which show that specific risk increases for men and women are far more distinct, justifying the selection of the correct answer.